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While this large retrospective study cannot fully prove causality, it provides robust real-world evidence that supports the safety of these medications

These medications mimic the natural hormone glucagon-like peptide-1 (GLP-1) to influence glucose regulation and appetite-related signaling

Rybelsus is an oral form of semaglutide approved for type 2 diabetes Recently, the FDA approved the first oral GLP-1 medication for weight loss, expanding treatment options for patients who prefer not to use injections Oral GLP-1 medications must be taken exactly as directed to ensure proper absorption and effectiveness

Ethics declarations Ethical approval Humans: This study in patients complies with the Declaration of Helsinki and has been approved by the local ethics committee